Recombinant Human ERAP1 Protein, MYC/DDK-tagged

• Cat.No.: ERAP1-2119H
• Product Overview: Recombinant human ERAP1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 107.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ERAP1 endoplasmic reticulum aminopeptidase 1 [ Homo sapiens ]
• Official Symbol: ERAP1
• Synonyms: A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
• Gene ID: 51752
• mRNA Refseq: NM_001040458
• Protein Refseq: NP_001035548
• MIM: 606832
• UniProt ID: Q9NZ08