Active Recombinant Human ERBB2 Protein, DDDDK-tagged
Cat.No. : | ERBB2-039H |
Product Overview : | Recombinant Human ERBB2 Protein(NP_004439.2) (Met1-Thr652) was expressed with five amino acids (DDDDK) at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | DDDDK |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA. Immobilized Human Her2/ERBB2 at 2 μg/ml (100 μl/well) can bind Herceptin, the EC50 of Herceptin is 7.0-30.0 ng/mL. 2. Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.3-1.5 μg/mL in the presence of 0.6 µg/mL Anti-ErbB2/Her2 Monoclonal Antibody. |
Molecular Mass : | The recombinant human ERBB2 consists 636 amino acids and predicts a molecular mass of 70 kDa. As a result of glycosylation, human ErbB2 migrates as an approximately 100-110 kDa protein in SDS-PAGE under reducing conditions. |
Protein length : | Met1-Thr652 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | ERBB2 |
Synonyms : | ERBB2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian); NGL, v erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); receptor tyrosine-protein kinase erbB-2; CD340; HER 2; HER2; NEU; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); NGL; TKR1; HER-2; MLN 19; HER-2/neu; |
Gene ID : | 2064 |
mRNA Refseq : | NM_001005862 |
Protein Refseq : | NP_001005862 |
MIM : | 164870 |
UniProt ID : | P04626 |
Products Types
◆ Recombinant Protein | ||
ERBB2-283H | Recombinant Human ERBB2 Protein, Fc-tagged | +Inquiry |
ERBB2-2546H | Recombinant Human ERBB2 protein(1101-1180 aa), C-His-tagged | +Inquiry |
ERBB2-13H | Active Recombinant Human ERBB2 Protein, Fc/His-tagged, Alexa Fluor® 488 conjugated | +Inquiry |
ERBB2-284H | Recombinant Human ERBB2 Protein, His-tagged | +Inquiry |
ERBB2-360H | Active Recombinant Human ERBB2 Protein, His & Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
ERBB2-2658HCL | Recombinant Human ERBB2 cell lysate | +Inquiry |
ERBB2-2008RCL | Recombinant Rhesus ERBB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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