Recombinant Human EXT1 Protein, GST-tagged

• Cat.No.: EXT1-3583H
• Product Overview: Human EXT1 full-length ORF ( NP_000118.2, 1 a.a. - 746 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 112.7 kDa
• AA Sequence: MQAKKRYFILLSAGSCLALLFYFGG LQFRASRSHSRREEHSGRNGLHHPS PDHFWPRFPDALRPFVPWDQLENED SSVHISPRQKRDANSSIYKGKKCRM ESCFDFTLCKKNGFKVYVYPQQKGE KIAESYQNILAAIEGSRFYTSDPSQ ACLFVLSLDTLDRDQLSPQYVHNLR SKVQSLHLWNNGRNHLIFNLYSGTW PDYTEDVGFDIGQAMLAKASISTEN FRPNFDVSIPLFSKDHPRTGGERGF LKFNTIPPLRKYMLVFKGKRYLTGI GSDTRNALYHVHNGEDVVLLTTCKH GKDWQKHKDSRCDRDNTEYEKYDYR EMLHNATFCLVPRGRRLGSFRFLEA LQAACVPVMLSNGWELPFSEVINWN QAAVIGDERLLLQIPSTIRSIHQDK ILALRQQTQFLWEAYFSSVEKIVLT TLEIIQDRIFKHISRNSLIWNKHPG GLFVLPQYSSYLGDFPYYYANLGLK PPSKFTAVIHAVTPLVSQSQPVLKL LVAAAKSQYCAQIIVLWNCDKPLPA KHRWPATAVPVVVIEGESKVMSSRF LPYDNIITDAVLSLDEDTVLSTTEV DFAFTVWQSFPERIVGYPARSHFWD NSKERWGYTSKWTNDYSMVLTGAAI YHKYYHYLYSHYLPASLKNMVDQLA NCEDILMNFLVSAVTKLPPIKVTQK KQYKETMMGQTSRASRWADPDHFAQ RQSCMNTFASWFGYMPLIHSQMRLD PVLFKDQVSILRKKYRDIERL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EXT1 exostosin 1 [ Homo sapiens ]
• Official Symbol: EXT1
• Synonyms: EXT1; exostosin 1; exostoses (multiple) 1 , Langer Giedion syndrome chromosome region , LGCR, LGS; exostosin-1; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase; ttv; exostoses (multiple) 1; multiple exostoses protein 1; putative tumor suppressor protein EXT1; Langer-Giedion syndrome chromosome region; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; EXT; LGS; TTV; LGCR; TRPS2
• Gene ID: 2131
• mRNA Refseq: NM_000127
• Protein Refseq: NP_000118
• MIM: 608177
• UniProt ID: Q16394