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Active Recombinant Human FCGR2B Protein, His-tagged, Biotinylated

Cat.No. : FCGR2B-259H
Product Overview : Biotinylated Recombinant Human FCGR2B Protein (Ala 46 - Pro 217) (P31994), fused with an Avi tag at the C-terminus, followed by a polyhistidine tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Ala 46
Form : Lyophilized from sterile PBS, pH7.4, 10% trehalose.
Bio-activity : Measured by its binding ability in a functional ELISA against immobilized Yervoy Ipilimumab (0.5 μg/well). The linear range is 2-62 ng/mL.
Molecular Mass : Recombinant Human FCGR2B Protein has a calculated MW of 23 kDa. The protein migrates as 29-32 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Protein length : Ala 46 - Pro 217
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) [ Homo sapiens ]
Official Symbol : FCGR2B
Synonyms : FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32) , FCG2, FCGR2; low affinity immunoglobulin gamma Fc region receptor II-b; CD32; CD32B; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); FCG2; FCGR2; IGFR2;
Gene ID : 2213
mRNA Refseq : NM_001002273
Protein Refseq : NP_001002273
MIM : 604590
UniProt ID : P31994
Chromosome Location : 1q23
Pathway : Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem;
Function : IgG binding; protein binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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