| Description : |
FGF-8b(FGF-8) is belonging to the FGF family, which is widely expressed during embryogenesis. There are four known alternate spliced forms of FGF-8: FGF-8a, FGF-8b, FGF-8e and FGF-8f. Proteins of this family play an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF-8b is required for normal brain, eye, ear and limb development during embryogenesis. It is also required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-8b shows the strongest receptor affinity and oncogenic transforming capacity. |
| Source : |
Human cells |
| Species : |
Human |
| Bio-activity : |
The activity was measured by its ability to stimulate the proliferation of 3T3 mouse fibroblast cells. |
| Molecular Mass : |
35-45 kDa |
| Endotoxin : |
<0.5 EU/ μg |
| Purity : |
High Purity, >95% by SDS-PAGE |
| Stability : |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution. |
| Storage Buffer : |
Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein |
| Reconstitution : |
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
