Recombinant Human FGFR2 Protein, DDK/His-tagged
Cat.No. : | FGFR2-791H |
Product Overview : | Recombinant Human FGFR2(Arg22-Glu377), transcript variant 1, fused with DDK/His tag at C-terminal was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
Source : | HEK293 cells |
Species : | Human |
Tag : | DDK/His |
Form : | 1 x PBS, pH7.4, 10% glycerol. |
Molecular Mass : | 42 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ] |
Official Symbol : | FGFR2 |
Synonyms : | FGFR2; fibroblast growth factor receptor 2; bacteria expressed kinase , BEK, CFD1, craniofacial dysostosis 1 , Jackson Weiss syndrome , JWS, keratinocyte growth factor receptor , KGFR; CD332; CEK3; Crouzon syndrome; ECT1; K SAM; Pfeiffer syndrome; TK14; TK25; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14; BEK; JWS; CFD1; KGFR; BFR-1; K-SAM; FLJ98662; |
Gene ID : | 2263 |
mRNA Refseq : | NM_000141 |
Protein Refseq : | NP_000132 |
MIM : | 176943 |
UniProt ID : | P21802 |
Products Types
◆ Recombinant Protein | ||
Fgfr2-135M | Recombinant Mouse Fgfr2 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGFR2-34H | Recombinant Active Human FGFR2 (N549K) Protein (285-end), N-GST-tagged | +Inquiry |
FGFR2-4128H | Recombinant Human FGFR2 Protein | +Inquiry |
FGFR2-33H | Recombinant Active Human FGFR2 (M420I) Protein (285-end), N-GST-tagged | +Inquiry |
FGFR2-705H | Active Recombinant Human FGFR2 protein(Met1-Glu377), His&hFc-tagged | +Inquiry |
◆ Lysates | ||
FGFR2-001MCL | Recombinant Mouse FGFR2 cell lysate | +Inquiry |
FGFR2-2578HCL | Recombinant Human FGFR2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0341 | FGFR2 Kinase (Human) Assay/Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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