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Recombinant Human FTL Protein, His-tagged

Cat.No. : FTL-800H
Product Overview : Recombinant Human FTL fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
Source : E. coli
Species : Human
Tag : His
Form : Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.5.
Molecular Mass : 24.5kD
AA Sequence : MNHKVHHHHHHMSSQIRQNYSTDVE AAVNSLVNLYLQASYTYLSLGFYFD RDDVALEGVSHFFRELAEEKREGYE RLLKMQNQRGGRALFQDIKKPAEDE WGKTPDAMKAAMALEKKLNQALLDL HALGSARTDPHLCDFLETHFLDEEV KLIKKMGDHLTNLHRLGGPEAGLGE YLFERLTLKHD*
Endotoxin : Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Name : FTL ferritin, light polypeptide [ Homo sapiens ]
Official Symbol : FTL
Synonyms : FTL; ferritin, light polypeptide; ferritin light chain; ferritin L subunit; ferritin L chain; ferritin light polypeptide like 3; L apoferritin; MGC71996; ferritin L-chain; ferritin light polypeptide-like 3; NBIA3;
Gene ID : 2512
mRNA Refseq : NM_000146
Protein Refseq : NP_000137
MIM : 134790
UniProt ID : P02792

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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What is the relationship between FTL protein and Alzheimer's disease? 12/28/2022

Current studies have shown that abnormal iron metabolism may be related to Alzheimer's disease, and FTL protein is one of the key proteins in iron metabolism. Therefore, FTL protein may be involved in the occurrence and progression of Alzheimer's disease. However, further research is needed to confirm the specific relationship.

What health problems can abnormal FTL protein levels cause? 03/24/2022

Abnormal levels of FTL protein can lead to a variety of health problems such as abnormal iron metabolism, anemia, neuropathy, heart disease, immune system abnormalities, and diabetes.

How can FTL proteins be used to treat certain diseases? 02/08/2022

Research is currently underway to develop new therapeutics using FTL protein as a target, such as improving symptoms of abnormal iron metabolism and related diseases by modulating the expression and function of FTL protein. However, further research and clinical trial validation are needed for specific applications.

How to Prevent FTL Protein-Related Diseases? 01/10/2022

Prevention of FTL protein-related diseases is mainly by maintaining a healthy lifestyle, such as a balanced diet, moderate exercise, and avoiding excessive intake of iron-containing drugs. In addition, regular check-ups and related examinations can also help to detect potential problems early.

What is the relationship between FTL protein and multiple sclerosis? 11/30/2021

Current studies have shown that multiple sclerosis may be related to abnormal iron metabolism, and FTL protein is one of the key proteins in iron metabolism, so it may be related to the occurrence and progression of multiple sclerosis. However, further research is needed to confirm the specific relationship.

How can lifestyle changes affect the function of FTL proteins? 12/21/2019

Lifestyle changes, such as healthy diet and moderate exercise, can affect the function and expression level of FTL protein. These changes can promote normal iron metabolism, which can help maintain good health.

Customer Reviews (3)

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Reviews
12/03/2022

    FTL has very good antigenicity and can induce target immune response.

    07/02/2022

      FTL has high sensitivity and strong specificity.

      05/16/2021

        The catalytic efficiency is high and the time consuming is short, which greatly saves the time of the experimental members.

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