Recombinant Human FTL Protein, His-tagged

• Cat.No.: FTL-800H
• Product Overview: Recombinant Human FTL fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.5.
• Molecular Mass: 24.5kD
• AA Sequence: MNHKVHHHHHHMSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD*
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: FTL ferritin, light polypeptide [ Homo sapiens ]
• Official Symbol: FTL
• Synonyms: FTL; ferritin, light polypeptide; ferritin light chain; ferritin L subunit; ferritin L chain; ferritin light polypeptide like 3; L apoferritin; MGC71996; ferritin L-chain; ferritin light polypeptide-like 3; NBIA3
• Gene ID: 2512
• mRNA Refseq: NM_000146
• Protein Refseq: NP_000137
• MIM: 134790
• UniProt ID: P02792