Recombinant Human GBA2 Protein, GST-tagged

• Cat.No.: GBA2-4767H
• Product Overview: Human GBA2 full-length ORF ( NP_065995.1, 1 a.a. - 927 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 131 kDa
• AA Sequence: MGTQDPGNMGTGVPASEQISCAKED PQVYCPEETGGTKDVQVTDCKSPED SRPPKETDCCNPEDSGQLMVSYEGK AMGYQVPPFGWRICLAHEFTEKRKP FQANNVSLSNMIKHIGMGLRYLQWW YRKTHVEKKTPFIDMINSVPLRQIY GCPLGGIGGGTITRGWRGQFCRWQL NPGMYQHRTVIADQFTVCLRREGQT VYQQVLSLERPSVLRSWNWGLCGYF AFYHALYPRAWTVYQLPGQNVTLTC RQITPILPHDYQDSSLPVGVFVWDV ENEGDEALDVSIMFSMRNGLGGGDD APGGLWNEPFCLERSGETVRGLLLH HPTLPNPYTMAVAARVTAATTVTHI TAFDPDSTGQQVWQDLLQDGQLDSP TGQSTPTQKGVGIAGAVCVSSKLRP RGQCRLEFSLAWDMPRIMFGAKGQV HYRRYTRFFGQDGDAAPALSHYALC RYAEWEERISAWQSPVLDDRSLPAW YKSALFNELYFLADGGTVWLEVLED SLPEELGRNMCHLRPTLRDYGRFGY LEGQEYRMYNTYDVHFYASFALIML WPKLELSLQYDMALATLREDLTRRR YLMSGVMAPVKRRNVIPHDIGDPDD EPWLRVNAYLIHDTADWKDLNLKFV LQVYRDYYLTGDQNFLKDMWPVCLA VMESEMKFDKDHDGLIENGGYADQT YDGWVTTGPSAYCGGLWLAAVAVMV QMAALCGAQDIQDKFSSILSRGQEA YERLLWNGRYYNYDSSSRPQSRSVM SDQCAGQWFLKACGLGEGDTEVFPT QHVVRALQTIFELNVQAFAGGAMGA VNGMQPHGVPDKSSVQSDEVWVGVV YGLAATMIQEGLTWEGFQTAEGCYR TVWERLGLAFQTPEAYCQQRVFRSL AYMRPLSIWAMQLALQQQQHKKASW PKVKQGTGLRTGPMFGPKEAMANLS PE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GBA2 glucosidase, beta (bile acid) 2 [ Homo sapiens ]
• Official Symbol: GBA2
• Synonyms: GBA2; glucosidase, beta (bile acid) 2; non-lysosomal glucosylceramidase; AD035; bile acid beta glucosidase; DKFZp762K054; KIAA1605; non lysosomal glucosylceramidase; NLGase; beta-glucosidase 2; glucosylceramidase 2; beta-glucocerebrosidase 2; bile acid beta-glucosidase; MGC16895
• Gene ID: 57704
• mRNA Refseq: NM_020944
• Protein Refseq: NP_065995
• MIM: 609471
• UniProt ID: Q9HCG7