Recombinant Human GLRX Protein, GST-tagged

• Cat.No.: GLRX-4975H
• Product Overview: Human GLRX full-length ORF ( AAH10965, 1 a.a. - 106 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 37.4 kDa
• AA Sequence: MAQEFVNCKIQPGKVVVFIKPTCPY CRRAQEILSQLPIKQGLLEFVDITA TNHTNEIQDYLQQLTGARTVPRVFI GKDCIGGCSDLVSLQQSGELLTRLK QIGALQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GLRX glutaredoxin (thioltransferase) [ Homo sapiens ]
• Official Symbol: GLRX
• Synonyms: GLRX; glutaredoxin (thioltransferase); glutaredoxin-1; GRX; GRX1; TTase-1; thioltransferase-1; FLJ43648; MGC117407
• Gene ID: 2745
• mRNA Refseq: NM_001118890
• Protein Refseq: NP_001112362
• MIM: 600443
• UniProt ID: P35754