Recombinant Human GNAQ Protein, His-tagged

• Cat.No.: GNAQ-32H
• Product Overview: Recombinant Human GNAQ Protein, fused to His-tag, was expressed in E. coli.

Specification

• Antigen Description: Recombinant Human GNAQ Protein
• Description: This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 50mM Tris, 300mM NaCl, pH8.0.
• Molecular Mass: 44.3 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMTLES IMACCLSEEAKEARRINDEIERQLR RDKRDARRELKLLLLGTGESGKSTF IKQMRIIHGSGYSDEDKRGFTKLVY QNIFTAMQAMIRAMDTLKIPYKYEH NKAHAQLVREVDVEKVSAFENPYVD AIKSLWNDPGIQECYDRRREYQLSD STKYYLNDLDRVADPAYLPTQQDVL RVRVPTTGIIEYPFDLQSVIFRMVD VGGQRSERRKWIHCFENVTSIMFLV ALSEYDQVLVESDNENRMEESKALF RTIITYPWFQNSSVILFLNKKDLLE EKIMYSHLVDYFPEYDGPQRDAQAA REFILKMFVDLNPDSDKIIYSHFTC ATDTENIRFVFAAVKDTILQLNLKE YNLV
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.17 mg/ml

Gene Information

• Gene Name: GNAQ G protein subunit alpha q [ Homo sapiens (human) ]
• Official Symbol: GNAQ
• Synonyms: GAQ; SWS; CMC1; G-ALPHA-q
• Gene ID: 2776
• mRNA Refseq: NM_002072
• Protein Refseq: NP_002063
• MIM: 600998
• UniProt ID: P50148