Recombinant Human HAVCR2 Protein, His-tagged
Cat.No. : | HAVCR2-2023H |
Product Overview : | Recombinant Human TIM-3 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ser22-Arg200) of human TIM-3 (Accession #NP_116171.3) fused with a 6×His tag at the C-terminus. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol. |
Protein length : | Ser22-Arg200 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 90% as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens ] |
Official Symbol : | HAVCR2 |
Synonyms : | HAVCR2; hepatitis A virus cellular receptor 2; FLJ14428; Tim 3; TIM3; TIMD3; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; KIM-3; Tim-3; TIMD-3; HAVcr-2; |
Gene ID : | 84868 |
mRNA Refseq : | NM_032782 |
Protein Refseq : | NP_116171 |
MIM : | 606652 |
UniProt ID : | Q8TDQ0 |
Products Types
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HAVCR2-956H | Recombinant Human HAVCR2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
HAVCR2-995MCL | Recombinant Mouse HAVCR2 cell lysate | +Inquiry |
HAVCR2-001CCL | Recombinant Cynomolgus HAVCR2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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