"HAVCR2" Related Products

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Recombinant Human HAVCR2 Protein, His-tagged

Cat.No.: HAVCR2-2023H
Product Overview: Recombinant Human TIM-3 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ser22-Arg200) of human TIM-3 (Accession #NP_116171.3) fused with a 6×His tag at the C-terminus.
Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Source: HEK293
Species: Human
Tag : His
Form: Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol.
Protein length: Ser22-Arg200
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 90% as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens ]
Official Symbol: HAVCR2
Synonyms: HAVCR2; hepatitis A virus cellular receptor 2; FLJ14428; Tim 3; TIM3; TIMD3; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; KIM-3; Tim-3; TIMD-3; HAVcr-2;
Gene ID: 84868
mRNA Refseq: NM_032782
Protein Refseq: NP_116171
MIM: 606652
UniProt ID: Q8TDQ0

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