Recombinant Human HBA2 Protein, GST-tagged

• Cat.No.: HBA2-4595H
• Product Overview: Human HBA2 full-length ORF ( AAH05931, 1 a.a. - 142 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 41.36 kDa
• AA Sequence: MVLSPADKTNVKAAWGKVGAHAGEY GAEALERMFLSFPTTKTYFPHFDLS HGSAQVKGHGKKVADALTNAVAHVD DMPNALSALSDLHAHKLRVDPVNFK LLSHCLLVTLAAHLPAEFTPAVHAS LDKFLASVSTVLTSKYR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HBA2 hemoglobin, alpha 2 [ Homo sapiens ]
• Official Symbol: HBA2
• Synonyms: HBA2; hemoglobin, alpha 2; hemoglobin subunit alpha; alpha globin; alpha-globin; alpha-2 globin; hemoglobin alpha chain; HBH
• Gene ID: 3040
• mRNA Refseq: NM_000517
• Protein Refseq: NP_000508
• MIM: 141850
• UniProt ID: P69905