Recombinant Human HERPUD1 Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | HERPUD1-5439H |
Product Overview : | HERPUD1 MS Standard C13 and N15-labeled recombinant protein (NP_001010990) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 40.7 kDa |
AA Sequence : | MESETEPEPV TLLVKSPNQR HRDLELSGDR GWSVGHLKAH LSRVYPERPR PEDQRLIYSG KLLLDHQCLR DLLPKVAEST EEPAGSNRGQ YPEDSSSDGL RQREVLRNLS SPGWENISRP EAAQQAFQGL GPGFSGYTPY GWLQLSWFQQ IYARQYYMQY LAATAASGAF VPPPSAQEIP VVSAPAPAPI HNQFPAENQP ANQNAAPQVV VNPGANQNLR MNAQGGPIVE EDDEINRDWL DWTYSAATFS VFLSILYFYS SLSRFLMVMG ATVVMYLHHV GWFPFRPRPV QNFPNDGPPP DVVNQDPNNN LQEGTDPETE DPNHLPPDRD VLDGEQTSPS FMSTAWLVFK TFFASLLPEG PPAIANTRTR PLEQKLISEE DLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 [ Homo sapiens (human) ] |
Official Symbol : | HERPUD1 |
Synonyms : | HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; HERP; KIAA0025; Mif1; SUP; MMS-inducible; methyl methanesulfonate (MMF)-inducible fragment protein 1; homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein; |
Gene ID : | 9709 |
mRNA Refseq : | NM_001010990 |
Protein Refseq : | NP_001010990 |
MIM : | 608070 |
UniProt ID : | Q15011 |
◆ Recombinant Protein
HERPUD1-4695H | Recombinant Human HERPUD1 Protein, GST-tagged | +Inquiry |
HERPUD1-628H | Recombinant Human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, His-tagged | +Inquiry |
HERPUD1-3151Z | Recombinant Zebrafish HERPUD1 | +Inquiry |
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◆ Lysates
HERPUD1-5584HCL | Recombinant Human HERPUD1 293 Cell Lysate | +Inquiry |
HERPUD1-5585HCL | Recombinant Human HERPUD1 293 Cell Lysate | +Inquiry |
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