"HRG" Related Products

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Recombinant Human HRG Protein, MYC/DDK-tagged

Cat.No.: HRG-2133H
Product Overview: Recombinant human HRG protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description: This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Nov 2014]
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 57.6 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: HRG histidine-rich glycoprotein [ Homo sapiens ]
Official Symbol: HRG
Synonyms: HPRG; HRGP; THPH11
Gene ID: 3273
mRNA Refseq: NM_000412
Protein Refseq: NP_000403
MIM: 142640
UniProt ID: P04196

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