Recombinant Human HSD3B7 Protein, GST-tagged HSD3B7-5081H

Recombinant Human HSD3B7 Protein, GST-tagged

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Recombinant Human HSD3B7 Protein, GST-tagged

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Cat.No. : HSD3B7-5081H
Product Overview : Human HSD3B7 full-length ORF ( NP_079469.2, 1 a.a. - 369 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 67.4 kDa
AA Sequence : MADSAQAQKLVYLVT GGCGFLGEHVVRMLL QREPRLGELRVFDQH LGPWLEELKTGPVRV TAIQGDVTQAHEVAA AVAGAHVVIHTAGLV DVFGRASPKTIHEVN VQGTRNVIEACVQTG TRFLVYTSSMEVVGP NTKGHPFYRGNEDTP YEAVHRHPYPCSKAL AEWLVLEANGRKVRG GLPLVTCALRPTGIY GEGHQIMRDFYRQGL RLGGWLFRAIPASVE HGRVYVGNVAWMHVL AARELEQRATLMGGQ VYFCYDGSPYRSYED FNMEFLGPCGLRLVG ARPLLPYWLLVFLAA LNALLQWLLRPLVLY APLLNPYTLAVANTT FTVSTDKAQRHFGYE PLFSWEDSRTRTILW VQAATGSAQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 [ Homo sapiens ]
Official Symbol : HSD3B7
Synonyms : HSD3B7; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; 3 beta-hydroxysteroid dehydrogenase type 7; C(27) 3BETA HSD; SDR11E3; short chain dehydrogenase/reductase family 11E; member 3; 3-beta-HSD VII; C(27)-3BETA-HSD; c(27) 3-beta-HSD; 3 beta-hydroxysteroid dehydrogenase type VII; 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; short chain dehydrogenase/reductase family 11E, member 3; CBAS1; PFIC4;
Gene ID : 80270
mRNA Refseq : NM_025193
Protein Refseq : NP_079469
MIM : 607764
UniProt ID : Q9H2F3

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