Recombinant Human HTRA4 Protein, GST-tagged

• Cat.No.: HTRA4-5227H
• Product Overview: Human HTRA4 full-length ORF ( AAH57765.1, 1 a.a. - 476 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.4 kDa
• AA Sequence: MIRPQLRTAGLGRCLLPGLLLLLVP VLWAGAEKLHTQPSCPAVCQPTRCP ALPTCALGTTPVFDLCRCCRVCPAA EREVCGGAQGQPCAPGLQCLQPLRP GFPSTCGCPTLGGAVCGSDRRTYPS MCALRAENRAARRLGKVPAVPVQWG NCGDTGTRSAGPLRRNYNFIAAVVE KVAPSVVHVQLWGRLLHGSRLVPVY SGSGFIVSEDGLIITNAHVVRNQQW IEVVLQNGARYEAVVKDIDLKLDLA VIKIESNAELPVLMLGRSSDLRAGE FVVALGSPFSLQNTATAGIVSTKQR GGKELGMKDSDMDYVQIDATINYGN SGGPLVNLDGDVIGVNSLRVTDGIS FAIPSDRVRQFLAEYHEHQMKGKAF SNKKYLGLQMLSLTVPLSEELKMHY PDFPDVSSGVYVCKVFEGTAAQSSG LRDHDVIVNINGKPITTTTDVVKAL DSDSLSMAVLRGKDNLLLTVIPETI N
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HTRA4 HtrA serine peptidase 4 [ Homo sapiens ]
• Official Symbol: HTRA4
• Synonyms: HTRA4; HtrA serine peptidase 4; probable serine protease HTRA4; FLJ90724
• Gene ID: 203100
• mRNA Refseq: NM_153692
• Protein Refseq: NP_710159
• MIM: 610700
• UniProt ID: P83105