Recombinant Human IL15 & IL15RA protein(Ile31-Asp96 & Asn22-Ser135), hFc-tagged
Cat.No. : | IL15 & IL15RA-1292H |
Product Overview : | Recombinant Human IL15RA (NP_002180.1) (Ile31-Asp96) linked with the Human IL15 (NP_000576.1, with mutation Asn 120 Asp) (Asn49-Ser162) by a peptide linker was expressed in HEK293, fused with the Fc region of human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-hFc |
Protein length : | Ile31-Asp96 & Asn22-Ser135 |
Form : | Lyophilized from sterile 50mMTris, 100mMNacl, 5%trehalose, 0.05%chaps, pH8.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant heterodimer of Human IL15RA & IL-15 (N120D) consists of 433 amino acids and predicts a molecular mass of 47.9 kDa. |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | IL15 interleukin 15 [ Homo sapiens ] |
Official Symbol : | IL15; IL15RA |
Synonyms : | IL15; interleukin 15; interleukin-15; IL 15; MGC9721; IL-15; |
Gene ID : | 3600 |
mRNA Refseq : | NM_000585 |
Protein Refseq : | NP_000576 |
MIM : | 600554 |
UniProt ID : | P40933 |
Products Types
◆ Lysates | ||
IL15-5248HCL | Recombinant Human IL15 293 Cell Lysate | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionTechniques discern IL15 and IL2 receptor binding kinetics.
Methods explore IL15's role in autoimmune disease mechanisms.
IL15 knockout models provide insights into its diverse functions.
IL15's influence on memory T cell differentiation investigated.
Immunofluorescence microscopy visualizes IL15 subcellular localization.
Approaches validate IL15's involvement in inflammatory responses.
IL15's role in NK cell cytotoxicity analyzed using assays.
ELISA measures IL15 secretion accurately.
qPCR quantifies IL15's impact on regulatory T cells.
Flow cytometry quantifies IL15-driven T-cell proliferation.
Customer Reviews (3)
Write a reviewMapping protein- interactions in DNA transcription for gene regulation.
Suitable for cytotoxicity assays.
Effective in NK cell activation.
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