Recombinant Human IL1B Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | IL1B-5955H |
Product Overview : | IL1B MS Standard C13 and N15-labeled recombinant protein (NP_000567) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 30.7 kDa |
AA Sequence : | MAEVPELASEMMAYYSGNEDDLFFE ADGPKQMKCSFQDLDLCPLDGGIQL RISDHHYSKGFRQAASVVVAMDKLR KMLVPCPQTFQENDLSTFFPFIFEE EPIFFDTWDNEAYVHDAPVRSLNCT LRDSQQKSLVMSGPYELKALHLQGQ DMEQQVVFSMSFVQGEESNDKIPVA LGLKEKNLYLSCVLKDDKPTLQLES VDPKNYPKKKMEKRFVFNKIEINNK LEFESAQFPNWYISTSQAENMPVFL GGTKGGQDITDFTMQFVSSTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | IL1B interleukin 1 beta [ Homo sapiens (human) ] |
Official Symbol : | IL1B |
Synonyms : | IL1B; interleukin 1, beta; interleukin-1 beta; IL 1B; IL1 BETA; IL1F2; IL-1 beta; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta; IL-1; IL1-BETA; |
Gene ID : | 3553 |
mRNA Refseq : | NM_000576 |
Protein Refseq : | NP_000567 |
MIM : | 147720 |
UniProt ID : | P01584 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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