Recombinant Human IL21R Protein, C-His-tagged
| Cat.No. : | IL21R-109H |
| Product Overview : | Recombinant Human IL21R Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | The IL-21 receptor (also designated IL-21R, NILR or novel interleukin receptor) is a type I cytokine receptor that forms a complex with the cytokine receptor γ chain, γc and mediates IL-21 signaling. IL-21R is present on the surface of natural killer, B and T cell populations with high levels in spleen and thymus. IL-21 and IL-21R influence lymphoid proliferation and early lymphoid development in the transition between innate and adaptive immunity. Tumor necrosis factor (TNF) upregulates IL-21R, and combinations of TNF and IL-21 can have synergistic effects on myeloma cell proliferation through pathways involving phosphorylation of JAK1, Stat3 and Erk1/2. The human IL-21R gene maps to chromosome 16p12.1 and encodes a 538 amino acid protein that is closely related to human IL2RB and shares 62% sequence identity to mouse Il21r. |
| Source : | E. coli |
| Species : | Human |
| Tag : | C-His |
| Molecular Mass : | ~23 kDa |
| AA Sequence : | CPDLVCYTDYLQTVICILEMWNLHP STLTLTWQDQYEELKDEATSCSLHR SAHNATHATYTCHMDVFHFMADDIF SVNITDQSGNYSQECGSFLLAESIK PAPPFNVTVTFSGQYNISWRSDYED PAFYMLKGKLQYELQYRNRGDPWAV SPRRKLISVDSRSVSLLPLEFRKDS SYELQVRAGPMPGSSYQGTWSEWSD PVIFQTQSEELKE |
| Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
| Notes : | For research use only, not for use in diagnostic procedure. |
| Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
| Concentration : | ≥0.5 mg/mL |
| Storage Buffer : | PBS, 4M Urea, pH7.4 |
| Gene Name : | IL21R interleukin 21 receptor [ Homo sapiens (human) ] |
| Official Symbol : | IL21R |
| Synonyms : | IL21R; interleukin 21 receptor; interleukin-21 receptor; CD360; IL-21R; IL-21 receptor; novel interleukin receptor; NILR; MGC10967; |
| Gene ID : | 50615 |
| mRNA Refseq : | NM_021798 |
| Protein Refseq : | NP_068570 |
| MIM : | 605383 |
| UniProt ID : | Q9HBE5 |
Products Types
| ◆ Recombinant Protein | ||
| Il21r-176M | Recombinant Mouse IL21R Protein (ECD), His-tagged(C-ter) | +Inquiry |
| Il21r-10582M | Recombinant Mouse Il21r Protein, His (Fc)-Avi-tagged | +Inquiry |
| IL21R-326H | Recombinant Human IL21R Protein, Fc-tagged | +Inquiry |
| Il21r-448M | Recombinant Mouse IL21 Receptor Protein, Fc-tagged | +Inquiry |
| IL21R-4441H | Recombinant Human IL21R Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Lysates | ||
| IL21R-2019HCL | Recombinant Human IL21R cell lysate | +Inquiry |
| IL21R-1442RCL | Recombinant Rat IL21R cell lysate | +Inquiry |
| IL21R-001CCL | Recombinant Cynomolgus IL21R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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