Recombinant Human IL31RA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IL31RA-3594H
• Product Overview: IL31RA MS Standard C13 and N15-labeled recombinant protein (NP_620586) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 86.3 kDa
• AA Sequence: MCIRQLKFFTTACVCECPQNILSPQ PSCVNLGMMWTWALWMLPSLCKFSL AALPAKPENISCVYYYRKNLTCTWS PGKETSYTQYTVKRTYAFGEKHDNC TTNSSTSENRASCSFFLPRITIPDN YTIEVEAENGDGVIKSHMTYWRLEN IAKTEPPKIFRVKPVLGIKRMIQIE WIKPELAPVSSDLKYTLRFRTVNST SWMEVNFAKNRKDKNQTYNLTGLQP FTEYVIALRCAVKESKFWSDWSQEK MGMTEEEAPCGLELWRVLKPAEADG RRPVRLLWKKARGAPVLEKTLGYNI WYYPESNTNLTETMNTTNQQLELHL GGESFWVSMISYNSLGKSPVATLRI PAIQEKSFQCIEVMQACVAEDQLVV KWQSSALDVNTWMIEWFPDVDSEPT TLSWESVSQATNWTIQQDKLKPFWC YNISVYPMLHDKVGEPYSIQAYAKE GVPSEGPETKVENIGVKTVTITWKE IPKSERKGIICNYTIFYQAEGGKGF SKTVNSSILQYGLESLKRKTSYIVQ VMANTSAGGTNGTSINFKTLSFSVF EIILITSLIGGGLLILIILTVAYGL KKPNKLTHLCWPTVPNPAESSIATW HGDDFKDKLNLKESDDSVNTEDRIL KPCSTPSDKLVIDKLVVNFGNVLQE IFTDEARTGQENNLGGEKNGYVTCP FRPDCPLGKSFEELPVSPEIPPRKS QYLRSRMPEGTRPEAKEQLLFSGQS LVPDHLCEEGAPNPYLKNSVTAREF LVSEKLPEHTKGEVTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IL31RA interleukin 31 receptor A [ Homo sapiens (human) ]
• Official Symbol: IL31RA
• Synonyms: IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; soluble type I cytokine receptor CRL3; GPL; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; MGC125346
• Gene ID: 133396
• mRNA Refseq: NM_139017
• Protein Refseq: NP_620586
• MIM: 609510
• UniProt ID: Q8NI17