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Recombinant Human IL31RA Protein, GST-tagged

Cat.No. : IL31RA-5191H
Product Overview : Human IL31RA full-length ORF ( ENSP00000297015, 1 a.a. - 732 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR; MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 109.4 kDa
AA Sequence : MMWTWALWMLPSLCKFSLAALPAKP ENISCVYYYRKNLTCTWSPGKETSY TQYTVKRTYAFGEKHDNCTTNSSTS ENRASCSFFLPRITIPDNYTIEVEA ENGDGVIKSHMTYWRLENIAKTEPP KIFRVKPVLGIKRMIQIEWIKPELA PVSSDLKYTLRFRTVNSTSWMEVNF AKNRKDKNQTYNLTGLQPFTEYVIA LRCAVKESKFWSDWSQEKMGMTEEE APCGLELWRVLKPAEADGRRPVRLL WKKARGAPVLEKTLGYNIWYYPESN TNLTETMNTTNQQLELHLGGESFWV SMISYNSLGKSPVATLRIPAIQEKS FQCIEVMQACVAEDQLVVKWQSSAL DVNTWMIEWFPDVDSEPTTLSWESV SQATNWTIQQDKLKPFWCYNISVYP MLHDKVGEPYSIQAYAKEGVPSEGP ETKVENIGVKTVTITWKEIPKSERK GIICNYTIFYQAEGGKGFSKTVNSS ILQYGLESLKRKTSYIVQVMASTSA GGTNGTSINFKTLSFSVFEIILITS LIGGGLLILIILTVAYGLKKPNKLT HLCWPTVPNPAESSIATWHGDDFKD KLNLKESDDSVNTEDRILKPCSTPS DKLVIDKLVVNFGNVLQEIFTDEAR TGQENNLGGEKNGYVTCPFRPDCPL GKSFEELPVSPEIPPRKSQYLRSRM PEGTRPEAKEQLLFSGQSLVPDHLC EEGAPNPYLKNSVTAREFLVSEKLP EHTKGEV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : IL31RA interleukin 31 receptor A [ Homo sapiens ]
Official Symbol : IL31RA
Synonyms : IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; soluble type I cytokine receptor CRL3; GPL; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; MGC125346;
Gene ID : 133396
mRNA Refseq : NM_001242636
Protein Refseq : NP_001229565
MIM : 609510
UniProt ID : Q8NI17

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Can recombinant IL31RA treat eczema? 12/03/2022

Recombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.

How is the research progress of IL31RA? 09/09/2022

The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.

Is recombinant IL31RA associated with chronic diseases? 06/30/2021

IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.

What are the clinical applications of IL31RA? 08/11/2020

The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.

Does IL31RA have serious side effects? 03/14/2020

The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.

What is the relationship between IL31RA and immune response? 04/08/2019

This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.

Customer Reviews (3)

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Reviews
08/06/2021

    Sensitivity and accuracy of the experiment were significantly improved by using this protein.

    03/28/2021

      The synthesis process is efficient and reliable, reducing experimental time and cost.

      04/23/2020

        Good stability and is suitable for long-term storage and use.

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