Recombinant Human IL31RA Protein, GST-tagged
Cat.No. : | IL31RA-5191H |
Product Overview : | Human IL31RA full-length ORF ( ENSP00000297015, 1 a.a. - 732 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR; MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 109.4 kDa |
AA Sequence : | MMWTWALWMLPSLCKFSLAALPAKP ENISCVYYYRKNLTCTWSPGKETSY TQYTVKRTYAFGEKHDNCTTNSSTS ENRASCSFFLPRITIPDNYTIEVEA ENGDGVIKSHMTYWRLENIAKTEPP KIFRVKPVLGIKRMIQIEWIKPELA PVSSDLKYTLRFRTVNSTSWMEVNF AKNRKDKNQTYNLTGLQPFTEYVIA LRCAVKESKFWSDWSQEKMGMTEEE APCGLELWRVLKPAEADGRRPVRLL WKKARGAPVLEKTLGYNIWYYPESN TNLTETMNTTNQQLELHLGGESFWV SMISYNSLGKSPVATLRIPAIQEKS FQCIEVMQACVAEDQLVVKWQSSAL DVNTWMIEWFPDVDSEPTTLSWESV SQATNWTIQQDKLKPFWCYNISVYP MLHDKVGEPYSIQAYAKEGVPSEGP ETKVENIGVKTVTITWKEIPKSERK GIICNYTIFYQAEGGKGFSKTVNSS ILQYGLESLKRKTSYIVQVMASTSA GGTNGTSINFKTLSFSVFEIILITS LIGGGLLILIILTVAYGLKKPNKLT HLCWPTVPNPAESSIATWHGDDFKD KLNLKESDDSVNTEDRILKPCSTPS DKLVIDKLVVNFGNVLQEIFTDEAR TGQENNLGGEKNGYVTCPFRPDCPL GKSFEELPVSPEIPPRKSQYLRSRM PEGTRPEAKEQLLFSGQSLVPDHLC EEGAPNPYLKNSVTAREFLVSEKLP EHTKGEV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | IL31RA interleukin 31 receptor A [ Homo sapiens ] |
Official Symbol : | IL31RA |
Synonyms : | IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; soluble type I cytokine receptor CRL3; GPL; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; MGC125346; |
Gene ID : | 133396 |
mRNA Refseq : | NM_001242636 |
Protein Refseq : | NP_001229565 |
MIM : | 609510 |
UniProt ID : | Q8NI17 |
Products Types
◆ Recombinant Protein | ||
IL31RA-2630M | Recombinant Mouse IL31RA Protein (19-499 aa), His-tagged | +Inquiry |
IL31RA-2312H | Recombinant Human IL31RA Protein, His-tagged | +Inquiry |
Il31ra-3520M | Recombinant Mouse Il31ra Protein, Myc/DDK-tagged | +Inquiry |
IL31RA-1920H | Recombinant Human IL31RA Protein, MYC/DDK-tagged | +Inquiry |
IL31RA-4515M | Recombinant Mouse IL31RA Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL31RA-854HCL | Recombinant Human IL31RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (6)
Ask a questionRecombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.
The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.
IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.
The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.
The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.
This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.
Customer Reviews (3)
Write a reviewSensitivity and accuracy of the experiment were significantly improved by using this protein.
The synthesis process is efficient and reliable, reducing experimental time and cost.
Good stability and is suitable for long-term storage and use.
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