Recombinant Human Interferon, Alpha 1

• Cat.No.: IFNA1-5280H
• Product Overview: Recombinant Human IFNA1is produced in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: At least 23 different variants of IFNA1 areknown. The individual proteins have molecular masses between 19-26 kDa andconsist of proteins with lengths of 156-166 and 172 amino acids. All IFNA1subtypes possess a common conserved sequence region between amino acidpositions 115-151 while the amino-terminal ends are variable. Many IFNA1subtypes differ in their sequences at only one or two positions. Naturallyoccurring variants also include proteins truncated by 10 amino acids at thecarboxy-terminal end.
• Form: Lyophilized from a0.2 um filtered solution in PBS, pH 7.4.
• Purity: > 96% by SDS-PAGEand HPLC analyses.
• Endotoxin Level: Less than 1EU/mL ofrHuIFN-α1b as determined by LAL method.
• Biological Activity: Fully biologicallyactive when compared to standard. The specific activity as determined in aviral resistance assay was found to be no less than 1.0 x 108IU/mg.
• Reconstitution: We recommend thatthis vial be briefly centrifuged prior to opening to bring the contents tothe bottom. Reconstitute in sterile distilled water or aqueous buffer to aconcentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned intoworking aliquots and stored at ≤20°C. Further dilutions should be made inappropriate buffered solutions.
• Storage: This lyophilizedpreparation is stable at 2-8°C, but should be kept at -20°C for long termstorage, preferably desiccated. Upon reconstitution, the preparation is stablefor up to one week at 2-8°C. For maximal stability, apportion thereconstituted preparation into working aliquots and store at -20°C to -80°C.Avoid repeated freeze/thaw cycles.
• OfficialSymbol: IFNA1

Gene Information

• Gene Name: IFNA1 interferon, alpha 1 [ Homosapiens ]
• Synonyms: IFNA1;interferon, alpha 1; IFL; IFN; IFNA; IFNA13; IFN-ALPHA;MGC138207; MGC138505; MGC138507; IFN-alphaD; interferon alpha-1/13; leIF D;IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; OTTHUMP00000021142;interferon alpha-D; interferon alpha 1b
• Gene ID: 3439
• mRNA Refseq: NM_024013
• Protein Refseq: NP_076918
• MIM: 139250
• UniProt ID: P01562
• Chromosome Location: 9p22
• Pathway: Autoimmune thyroiddisease; Cytokine Signaling in Immune system; Cytokine-cytokine receptorinteraction; Cytosolic DNA-sensing pathway; Factors involved in megakaryocytedevelopment and platelet production; Hemostasis; Hepatitis C; Herpes simplexinfection; IL-2 Signaling Pathway; Immune System; Interferon Signaling