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Recombinant Human Interferon, Alpha 1

Cat.No. : IFNA1-5280H
Product Overview : Recombinant Human IFNA1is produced in E. coli.
  • Specification
  • Gene Information
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Cat. No. : IFNA1-5280H
Description : At least 23 different variants of IFNA1 areknown. The individual proteins have molecular masses between 19-26 kDa andconsist of proteins with lengths of 156-166 and 172 amino acids. All IFNA1subtypes possess a common conserved sequence region between amino acidpositions 115-151 while the amino-terminal ends are variable. Many IFNA1subtypes differ in their sequences at only one or two positions. Naturallyoccurring variants also include proteins truncated by 10 amino acids at thecarboxy-terminal end.
Source : E. coli
Species : Human
Form : Lyophilized from a0.2 um filtered solution in PBS, pH 7.4.
Purity : > 96% by SDS-PAGEand HPLC analyses.
Endotoxin Level : Less than 1EU/mL ofrHuIFN-α1b as determined by LAL method.
Biological Activity : Fully biologicallyactive when compared to standard. The specific activity as determined in aviral resistance assay was found to be no less than 1.0 x 108IU/mg.
Reconstitution : We recommend thatthis vial be briefly centrifuged prior to opening to bring the contents tothe bottom. Reconstitute in sterile distilled water or aqueous buffer to aconcentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned intoworking aliquots and stored at ≤20°C. Further dilutions should be made inappropriate buffered solutions.
Storage : This lyophilizedpreparation is stable at 2-8°C, but should be kept at -20°C for long termstorage, preferably desiccated. Upon reconstitution, the preparation is stablefor up to one week at 2-8°C. For maximal stability, apportion thereconstituted preparation into working aliquots and store at -20°C to -80°C.Avoid repeated freeze/thaw cycles.
OfficialSymbol : IFNA1
Gene Name : IFNA1 interferon, alpha 1 [ Homosapiens ]
Synonyms : IFNA1;interferon, alpha 1; IFL; IFN; IFNA; IFNA13; IFN-ALPHA;MGC138207; MGC138505; MGC138507; IFN-alphaD; interferon alpha-1/13; leIF D;IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; OTTHUMP00000021142;interferon alpha-D; interferon alpha 1b
Gene ID : 3439
mRNA Refseq : NM_024013
Protein Refseq : NP_076918
MIM : 139250
UniProt ID : P01562
Chromosome Location : 9p22
Pathway : Autoimmune thyroiddisease; Cytokine Signaling in Immune system; Cytokine-cytokine receptorinteraction; Cytosolic DNA-sensing pathway; Factors involved in megakaryocytedevelopment and platelet production; Hemostasis; Hepatitis C; Herpes simplexinfection; IL-2 Signaling Pathway; Immune System; Interferon Signaling

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.



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