Recombinant Human ITPA Protein, GST-tagged

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Recombinant Human ITPA Protein, GST-tagged

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Cat.No. : ITPA-4952H
Product Overview : Human ITPA full-length ORF ( AAH10138, 1 a.a. - 194 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. The encoded protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency. Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript variants have been identified which are probably regulatory rather than protein-coding. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 47.08 kDa
AA Sequence : MAASLVGKKIVFVTG NAKKLEEVVQILGDK FPCTLVAQKIDLPEY QGEPDEISIQKCQEA VRQVQGPVLVEDTCL CFNALGGLPGPYIKW FLEKLKPEGLHQLLA GFEDKSAYALCTFAL STGDPSQPVRLFRGR TSGRIVAPRGCQDFG WDPCFQPDGYEQTYA EMPKAEKNAVSHRFR ALLELQEYFGSLAA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) [ Homo sapiens ]
Official Symbol : ITPA
Synonyms : ITPA; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); C20orf37; inosine triphosphate pyrophosphatase; dJ794I6.3; HLC14 06 P; NTPase; My049 protein; inosine triphosphatase-A; putative oncogene protein HLC14-06-P; nucleoside triphosphate diphosphatase; nucleoside-triphosphate diphosphatase; non-standard purine NTP pyrophosphatase; nucleoside-triphosphate pyrophosphatase; non-canonical purine NTP pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; HLC14-06-P;
Gene ID : 3704
mRNA Refseq : NM_033453
Protein Refseq : NP_258412
MIM : 147520
UniProt ID : Q9BY32

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