Recombinant Human KRT19 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: KRT19-244H
• Product Overview: KRT19 MS Standard C13 and N15-labeled recombinant protein (NP_002267) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 43.9 kDa
• AA Sequence: MTSYSYRQSSATSSFGGLGGGSVRF GPGVAFRAPSIHGGSGGRGVSVSSA RFVSSSSSGGYGGGYGGVLTASDGL LAGNEKLTMQNLNDRLASYLDKVRA LEAANGELEVKIRDWYQKQGPGPSR DYSHYYTTIQDLRDKILGATIENSR IVLQIDNARLAADDFRTKFETEQAL RMSVEADINGLRRVLDELTLARTDL EMQIEGLKEELAYLKKNHEEEISTL RGQVGGQVSVEVDSAPGTDLAKILS DMRSQYEVMAEQNRKDAEAWFTSRT EELNREVAGHTEQLQMSRSEVTDLR RTLQGLEIELQSQLSMKAALEDTLA ETEARFGAQLAHIQALISGIEAQLG DVRADSERQNQEYQRLMDIKSRLEQ EIATYRSLLEGQEDHYNNLSASKVL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KRT19 keratin 19 [ Homo sapiens (human) ]
• Official Symbol: KRT19
• Synonyms: KRT19; keratin 19; keratin, type I cytoskeletal 19; 40 kDa keratin intermediate filament; CK19; cytokeratin 19; K1CS; K19; keratin; type I cytoskeletal 19; type I; 40 kd; MGC15366; CK-19; keratin-19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament
• Gene ID: 3880
• mRNA Refseq: NM_002276
• Protein Refseq: NP_002267
• MIM: 148020
• UniProt ID: P08727