Recombinant Human MAP2K2 Protein, MYC/DDK-tagged
Cat.No. : | MAP2K2-253H |
Product Overview : | Recombinant human MAP2K2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 44.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | mitogen-activated protein kinase kinase 2 [ Homo sapiens ] |
Official Symbol : | MAP2K2 |
Synonyms : | CFC4; MAPKK2; MEK2; MKK2; PRKMK2 |
Gene ID : | 5605 |
mRNA Refseq : | NM_030662.3 |
Protein Refseq : | NP_109587.1 |
MIM : | 601263 |
UniProt ID : | P36507 |
Products Types
◆ Recombinant Protein | ||
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MAP2K2-0226H | Recombinant Human MAP2K2 Protein (E55-V400), Tag Free | +Inquiry |
MAP2K2-1353H | Recombinant Human MAP2K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP2K2-0227H | Recombinant Human MAP2K2 Protein (E55-V400), His tagged | +Inquiry |
MAP2K2-3216R | Recombinant Rat MAP2K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MAP2K2-613HCL | Recombinant Human MAP2K2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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