Recombinant Human MAP4K5 Protein, MYC/DDK-tagged

• Cat.No.: MAP4K5-388H
• Product Overview: Recombinant human MAP4K5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 94.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: mitogen-activated protein kinase kinase kinase kinase 5 [ Homo sapiens ]
• Official Symbol: MAP4K5
• Synonyms: GCKR; KHS; KHS1; MAPKKKK5
• Gene ID: 11183
• mRNA Refseq: NM_006575.4
• Protein Refseq: NP_006566.2
• MIM: 604923
• UniProt ID: Q9Y4K4