| Description : |
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
95.1 kDa |
| AA Sequence : |
MEAPLRPAADILRRNPQQDYELVQR VGSGTYGDVYKARNVHTGELAAVKI IKLEPGDDFSLIQQEIFMVKECKHC NIVAYFGSYLSREKLWICMEYCGGG SLQDIYHVTGPLSELQIAYVCRETL QGLAYLHTKGKMHRDIKGANILLTD HGDVKLADFGVAAKITATIAKRKSF IGTPYWMAPEVAAVEKNGGYNQLCD IWAVGITAIELGELQPPMFDLHPMR ALFLMSKSNFQPPKLKDKTKWSSTF HNFVKIALTKNPKKRPTAERLLTHT FVAQPGLSRALAVELLDKVNNPDNH AHYTEADDDDFEPHAIIRHTIRSTN RNARAERTASEINFDKLQFEPPLRK ETEARDEMGLSSDPNFMLQWNPFVD GANTGKSTSKRAIPPPLPPKPRISS YPEDNFPDEEKASTIKHCPDSESRA PQILRRQSSPSCGPVAETSSIGNGD GISKLMSENTEGSAQAPQLPRKKDK RDFPKPAINGLPPTPKVLMGACFSK VFDGCPLKINCATSWIHPDTKDQYI IFGTEDGIYTLNLNELHEATMEQLF PRKCTWLYVINNTLMSLSEGKTFQL YSHNLIALFEHAKKPGLAAHIQTHR FPDRILPRKFALTTKIPDTKGCHKC CIVRNPYTGHKYLCGALQSGIVLLQ WYEPMQKFMLIKHFDFPLPSPLNVF EMLVIPEQEYPMVCVAISKGTESNQ VVQFETINLNSASSWFTEIGAGSQQ LDSIHVTQLERDTVLVCLDKFVKIV NLQGKLKSSKKLASELSFDFRIESV VCLQDSVLAFWKHGMQGKSFKSDEV TQEISDETRVFRLLGSDRVVVLESR PTENPTAHSNLYILAGHENSYTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
