Recombinant Human MASP1 Protein (His20-Arg728), C-His tagged
Cat.No. : | MASP1-3743H |
Product Overview : | Recombinant human MASP1 (His20-Arg728) fused with the C-terminal His tag was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 78.1 kDa |
Protein Length : | His20-Arg728 |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | MASP1 MBL associated serine protease 1 [ Homo sapiens (human) ] |
Official Symbol : | MASP1 |
Synonyms : | MASP1; MBL associated serine protease 1; 3MC1; MAP1; MASP; RaRF; CRARF; MAP-1; MASP3; MAp44; PRSS5; CRARF1; MASP-3; mannan-binding lectin serine protease 1; C4/C2 activating component of Ra-reactive factor; Ra-reactive factor serine protease p100; complement factor MASP-3; complement-activating component of Ra-reactive factor; mannan binding lectin serine peptidase 1; mannose-associated serine protease 1; mannose-binding lectin-associated serine protease 1; mannose-binding protein-associated serine protease; serine protease 5; EC 3.4.21.- |
Gene ID : | 5648 |
mRNA Refseq : | NM_139125 |
Protein Refseq : | NP_624302 |
MIM : | 600521 |
UniProt ID : | P48740 |
Products Types
◆ Recombinant Protein | ||
MASP1-1451H | Recombinant Human MASP1 Protein (20-699 aa), His-tagged | +Inquiry |
MASP1-02H | Recombinant Human MASP1 Protein, Myc/DDK-tagged | +Inquiry |
MASP1-648H | Recombinant Human MASP1 Protein (20-699 aa), His-SUMO-tagged | +Inquiry |
MASP1-5379M | Recombinant Mouse MASP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MASP1-3248R | Recombinant Rat MASP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MASP1-4461HCL | Recombinant Human MASP1 293 Cell Lysate | +Inquiry |
MASP1-4460HCL | Recombinant Human MASP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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