Active Recombinant Human MELK Protein, GST-tagged

• Cat.No.: MELK-4448H
• Product Overview: Human MELK (NP_055606.1, 1 a.a. - 493 a.a.) partial recombinant protein with GST tag expressed in Escherichia coli

Specification

• Description: MELK (Maternal Embryonic Leucine Zipper Kinase) is a Protein Coding gene. Among its related pathways are Neuroscience. GO annotations related to this gene include calcium ion binding and protein kinase activity. An important paralog of this gene is SNRK.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Liquid
• Bio-activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000.
  Substrate: GS peptide.
  ATP: 100 µM.
• Molecular Mass: 84 kDa
• Purity: 62 % by SDS-PAGE/CBB staining.
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)

Gene Information

• Gene Name: MELK maternal embryonic leucine zipper kinase [ Homo sapiens ]
• Official Symbol: MELK
• Synonyms: MELK; maternal embryonic leucine zipper kinase; KIAA0175; pEg3 kinase; protein kinase Eg3; protein kinase PK38; tyrosine-protein kinase MELK; HPK38
• Gene ID: 9833
• mRNA Refseq: NM_001256685
• Protein Refseq: NP_001243614
• MIM: 607025
• UniProt ID: Q14680