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Recombinant Human MIF Protein

Cat.No. : MIF-018H
Product Overview : Recombinant Human MIF protein without tag was expressed in E.coli
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Source : E. coli
Species : Human
Molecular Mass : 12.6 kDa
Purity : ≥95% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to tautomerize 1 nmole of L-dopachrome (5,6-dihydroxyindole-2-carboxylate methyl ester) per minute at 21 centigrade in 40 mM Bis-Tris, pH 6.2, 0.8 mM EDTA, containing 260 μM L-dopachrome methyl ester, and 510 μM sodium periodate.
Stability : ≥ 6 months
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
Gene Name : MIF macrophage migration inhibitory factor [ Homo sapiens (human) ]
Official Symbol : MIF
Synonyms : MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; macrophage migration inhibitory factor; L-dopachrome isomerase; L-dopachrome tautomerase; epididymis secretory sperm binding protein; macrophage migration inhibitory factor (glycosylation-inhibiting factor); phenylpyruvate tautomerase; EC 5.3.2.1
Gene ID : 4282,
mRNA Refseq : NM_002415
Protein Refseq : NP_002406
MIM : 153620
UniProt ID : P14174

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does MIF contribute to autoimmune diseases? 07/30/2022

MIF can promote inflammation and immune responses, contributing to autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus.

How does MIF influence neuroinflammation? 10/01/2021

MIF is involved in the regulation of neuroinflammation and has implications in neurodegenerative diseases like Alzheimer's.

What are some conditions where MIF is implicated in clinical applications? 12/22/2019

MIF is implicated in conditions like autoimmune diseases, sepsis, and cancer.

Can MIF be a potential therapeutic target in autoimmune diseases? 08/20/2019

Yes, targeting MIF with drugs or antibodies is being explored as a potential treatment for autoimmune diseases.

What are some other clinical applications of MIF? 02/26/2019

MIF is also studied in the context of cardiovascular diseases, neuroinflammation, and wound healing.

Customer Reviews (3)

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Reviews
12/05/2022

    The cost-effectiveness of the MIF protein, competitive pricing, and the availability of bulk purchase options provided by the manufacturer also align with my budget considerations, allowing me to optimize my resources.

    10/13/2016

      the manufacturer's commitment to delivering the MIF protein in a timely manner is greatly appreciated.

      06/06/2016

        the excellent technical support provided by the manufacturer is of immense value to me.

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