Recombinant Human MKNK1 Protein, Myc/DDK-tagged

• Cat.No.: MKNK1-01H
• Product Overview: Recombinant human MKNK1 protein with a C-terminal Myc/DDK-tag was expressed in HEK293T.

Specification

• Description: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade
• Concentration: > 50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: MKNK1 MAPK interacting serine/threonine kinase 1 [ Homo sapiens (human) ]
• Official Symbol: MKNK1
• Synonyms: MKNK1; MAPK interacting serine/threonine kinase 1; MNK1; MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1
• Gene ID: 8569
• mRNA Refseq: NM_001135553
• Protein Refseq: NP_001129025
• MIM: 606724
• UniProt ID: Q9BUB5