| Description : |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67.9 kDa |
| AA Sequence : |
MALPTARPLLGSCGTPALGSLLFLL FSLGWVQPSRTLAGETGQAAPLDGV LANPPNISSLSPRQLLGFPCAEVSG LSTERVRELAVALAQKNVKLSTEQL RCLAHRLSEPPEDLDALPLDLLLFL NPDAFSGPQACTRFFSRITKANVDL LPRGAPERQRLLPAALACWGVRGSL LSEADVRALGGLACDLPGRFVAESA EVLLPRLVSCPGPLDQDQQEAARAA LQGGGPPYGPPSTWSVSTMDALRGL LPVLGQPIIRSIPQGIVAAWRQRSS RDPSWRQPERTILRPRFRREVEKTA CPSGKKAREIDESLIFYKKWELEAC VDAALLATQMDRVNAIPFTYEQLDV LKHKLDELYPQGYPESVIQHLGYLF LKMSPEDIRKWNVTSLETLKALLEV NKGHEMSPQVATLIDRFVKGRGQLD KDTLDTLTAFYPGYLCSLSPEELSS VPPSSIWAVRPQDLDTCDPRQLDVL YPKARLAFQNMNGSEYFVKIQSFLG GAPTEDLKALSQQNVSMDLATFMKL RTDAVLPLTVAEVQKLLGPHVEGLK AEERHRPVRDWILRQRQDDLDTLGL GLQGGIPNGYLVLDLSVQEALSGTP CLLGPGPVLTVLALLLASTLATRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
