Recombinant Human MYL12B Protein, GST-tagged

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Recombinant Human MYL12B Protein, GST-tagged

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Cat.No. : MYL12B-5548H
Product Overview : Human MRLC2 full-length ORF ( NP_291024.1, 1 a.a. - 172 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 46.2 kDa
AA Sequence : MSSKKAKTKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS LGKNPTDAYL DAMMNEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEATGTIQE DYLRELLTTM GDRFTDEEVD ELYREAPIDK KGNFNYIEFT RILKHGAKDK DD
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MYL12B myosin light chain 12B [ Homo sapiens (human) ]
Official Symbol : MYL12B
Synonyms : MYL12B; myosin light chain 12B; MLC-B; MRLC2; myosin regulatory light chain 12B; MLC-2; MLC-2A; MLC20; SHUJUN-1; myosin regulatory light chain 2; myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain MRLC2; myosin, light chain 12B, regulatory
Gene ID : 103910
mRNA Refseq : NM_001144944
Protein Refseq : NP_001138416
MIM : 609211
UniProt ID : O14950

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