Recombinant Human MYST1 Protein, GST-tagged

• Cat.No.: MYST1-5863H
• Product Overview: Human MYST1 full-length ORF ( AAH37773.1, 1 a.a. - 467 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 79.5 kDa
• AA Sequence: MAAQGAAAAVAAGTSGVAGEGEPGP GENAAAEGTAPSPGRVSPPTPARGE PEVTVEIGETYLCRRPDSTWHSAEV IQSRVNDQEGREEFYVHYVGFNRRL DEWVDKNRLALTKTVKDAVQKNSEK YLSELAEQPERKITRNQKRKHDEIN HVQKTYAEMDPTTAALEKEHEAITK VKYVDKIHIGNYEIDAWYFSPFPED YGKQPKLWLCEYCLKYMKYEKSYRF HLGQCQWRQPPGKEIYRKSNISVYE VDGKDHKIYCQNLCLLAKLFLDHKT LYFDVEPFVFYILTEVDRQGAHIVG YFSKEKESPDGNNVACILTLPPYQR RGYGKFLIAFSYELSKLESTVGSPE KPLSDLGKLSYRSYWSWVLLEILRD FRGTLSIKDLSQMTSITQNDIISTL QSLNMVKYWKGQHVICVTPKLVEEH LKSAQYKKPPITGGWGAAVCRGRWG SVSMWTGRSQGLLIAVT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KAT8 lysine acetyltransferase 8 [ Homo sapiens (human) ]
• Official Symbol: MYST1
• Synonyms: KAT8; lysine acetyltransferase 8; MOF; hMOF; MYST1; ZC2HC8; histone acetyltransferase KAT8; K(lysine) acetyltransferase 8; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST-1; histone acetyltransferase MYST1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1; EC 2.3.1.48
• Gene ID: 84148
• mRNA Refseq: NM_032188
• Protein Refseq: NP_115564
• MIM: 609912
• UniProt ID: Q9H7Z6