Recombinant Human NTRK2 protein, Fc-tagged
Cat.No. : | NTRK2-159H |
Product Overview : | Recombinant Human NTRK2 protein (Cys32-His430), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2/TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2/Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is "ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate". NTRK2/TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 70.4 kDa. The protein migrates as 86-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 399 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >98% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | NTRK2 |
Official Symbol : | NTRK2 |
Synonyms : | NTRK2; neurotrophic tyrosine kinase, receptor, type 2; BDNF/NT-3 growth factors receptor; TRKB; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B; trk-B; GP145-TrkB |
Gene ID : | 4915 |
mRNA Refseq : | NM_001007097 |
Protein Refseq : | NP_001007098 |
MIM : | 600456 |
UniProt ID : | Q16620 |
Products Types
◆ Recombinant Protein | ||
NTRK2-379H | Recombinant Human NTRK2 Protein, His-tagged | +Inquiry |
Ntrk2-4523M | Recombinant Mouse Ntrk2 Protein, Myc/DDK-tagged | +Inquiry |
NTRK2-4467H | Recombinant Human NTRK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK2-470H | Recombinant Human NTRK2 Protein, Fc-tagged | +Inquiry |
NTRK2-3764R | Recombinant Rat NTRK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NTRK2-1843MCL | Recombinant Mouse NTRK2 cell lysate | +Inquiry |
NTRK2-2683HCL | Recombinant Human NTRK2 cell lysate | +Inquiry |
NTRK2-1300RCL | Recombinant Rat NTRK2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1547 | U2OS TrkB Bioassay Kit | +Inquiry |
Kit-1629 | TrkB Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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