| Description : |
This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
68.1 kDa |
| Protein length : |
1 a.a. - 373 a.a. |
| AA Sequence : |
MKLINGKKQTFPWFGMDIGGTLVKL VYFEPKDITAEEEQEEVENLKSIRK YLTSNTAYGKTGIRDVHLELKNLTM CGRKGNLHFIRFPSCAMHRFIQMGS EKNFSSLHTTLCATGGGAFKFEEDF RMIADLQLHKLDELDCLIQGLLYVD SVGFNGKPECYYFENPTNPELCQKK PYCLDNPYPMLLVNMGSGVSILAVY SKDNYKRVTGTSLGGGTFLGLCCLL TGCETFEEALEMAAKGDSTNVDKLV KDIYGGDYERFGLQGSAVASSFGNM MSKEKRDSISKEDLARATLVTITNN IGSIARMCALNENIDRVVFVGNFLR INMVSMKLLAYAMDFWSKGQLKALF LEHEGYFGAVGALLELFKMTDDK |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
