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Recombinant Human PAX6 Protein, His-tagged

Cat.No. : PAX6-148H
Product Overview : Recombinant Human PAX6, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 48 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PAX6 paired box 6 [ Homo sapiens ]
Official Symbol : PAX6
Synonyms : PAX6; paired box 6; AN2, paired box gene 6 (aniridia, keratitis); paired box protein Pax-6; AN; aniridia; keratitis; D11S812E; WAGR; oculorhombin; aniridia type II protein; paired box homeotic gene-6; AN2; MGDA; MGC17209;
Gene ID : 5080
mRNA Refseq : NM_001604
Protein Refseq : NP_001595
MIM : 607108
UniProt ID : P26367

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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