Recombinant Human PIGR Protein, His-tagged

• Cat.No.: PIGR-209H
• Product Overview: Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor is produced by Human 293 Cells. The target gene encoding K19-R638 is expressed with a 8His tag at the C terminus.

Specification

• Description: Polymeric Immunoglobulin Receptor (pIgR) is a type I transmembrane glycoprotein. pIgR is expressed by secretory epithelial cells with five Ig-like domains in the extracellular region, and transfer to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs and separates the extracellular (known as the secretory component) from the transmembrane segment.
• Source: Human Cells
• Species: Human
• Tag: His
• Form: Lyophilized frum a 0.2 um filtered solution of PBS, pH7.4
• AA Sequence: K19-R638
• Endotoxin: Less than 0.1 EU/ug.
• Shipping: Ambient

Gene Information

• Gene Name: PIGR polymeric immunoglobulin receptor [ Homo sapiens (human) ]
• Official Symbol: PIGR
• Synonyms: Polymeric Immunoglobulin Receptor; PIgR; Poly-Ig Receptor; Hepatocellular Carcinoma-Associated Protein TB6
• Gene ID: 5284
• mRNA Refseq: NM_002644.4
• Protein Refseq: NP_002635.2
• MIM: 173880
• UniProt ID: P01833