Active Recombinant Human PIP4K2B protein, GST-tagged
Cat.No. : | PIP4K2B-168H |
Product Overview : | Recombinant Human PIP4K2B fused with an N-terminal GST tag was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase, type II, beta) catalyzes the phosphorylation of phospha-tidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. PIP4K2B is a member of the phosphatidylinositol-5-phosphate 4-kinase family. PIP5K2B interacts specifically with the juxtamembrane region of the p55 TNF receptor and that PIP5K2B activity is increased in mammalian cells by treatment with TNF-alpha. PIP5P4KB plays a role in determining insulin sensitivity and adiposity. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 5250 nmol/min/mg |
Molecular Mass : | 73 kDa |
Purity : | >95% |
Applications : | Kinase Assay |
Stability : | 1 year at -70 centigrade from the date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta [ Homo sapiens ] |
Official Symbol : | PIP4K2B |
Synonyms : | PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; phosphatidylinositol 4 phosphate 5 kinase, type II, beta , PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PIP5KIIB; PIP5KIIbeta; PIP4KII-beta; PTDINS(4)P-5-kinase; PI(5)P 4-kinase type II beta; diphosphoinositide kinase 2-beta; ptdIns(5)P-4-kinase isoform 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; PI5P4KB; PIP5K2B; |
Gene ID : | 8396 |
mRNA Refseq : | NM_003559 |
Protein Refseq : | NP_003550 |
MIM : | 603261 |
UniProt ID : | P78356 |
Chromosome Location : | 17q21.2 |
Pathway : | 3-phosphoinositide biosynthesis, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Phosphatidylinositol signaling system, organism-specific biosystem; Phosphatidylinositol signaling system, conserved biosystem; |
Function : | 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; ATP binding; nucleotide binding; receptor signaling protein activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
PIP4K2B-0806H | Recombinant Human PIP4K2B Protein (S2-T416), Tag Free | +Inquiry |
PIP4K2B-0807H | Recombinant Human PIP4K2B Protein (S2-T416), His tagged | +Inquiry |
PIP4K2B-4130R | Recombinant Rat PIP4K2B Protein, His (Fc)-Avi-tagged | +Inquiry |
Pip4k2b-359M | Recombinant Mouse Pip4k2b Protein, MYC/DDK-tagged | +Inquiry |
PIP4K2B-188H | Recombinant Human PIP4K2B | +Inquiry |
◆ Lysates | ||
PIP4K2B-1353HCL | Recombinant Human PIP4K2B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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