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Active Recombinant Human PIP4K2B protein, GST-tagged

Cat.No. : PIP4K2B-168H
Product Overview : Recombinant Human PIP4K2B fused with an N-terminal GST tag was expressed in Insect cells.
  • Specification
  • Gene Information
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Description : PIP4K2B (phosphatidylinositol-5-phosphate 4-kinase, type II, beta) catalyzes the phosphorylation of phospha-tidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. PIP4K2B is a member of the phosphatidylinositol-5-phosphate 4-kinase family. PIP5K2B interacts specifically with the juxtamembrane region of the p55 TNF receptor and that PIP5K2B activity is increased in mammalian cells by treatment with TNF-alpha. PIP5P4KB plays a role in determining insulin sensitivity and adiposity.
Source : Insect cells
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 5250 nmol/min/mg
Molecular Mass : 73 kDa
Purity : >95%
Applications : Kinase Assay
Stability : 1 year at -70 centigrade from the date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name : PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta [ Homo sapiens ]
Official Symbol : PIP4K2B
Synonyms : PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; phosphatidylinositol 4 phosphate 5 kinase, type II, beta , PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PIP5KIIB; PIP5KIIbeta; PIP4KII-beta; PTDINS(4)P-5-kinase; PI(5)P 4-kinase type II beta; diphosphoinositide kinase 2-beta; ptdIns(5)P-4-kinase isoform 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; PI5P4KB; PIP5K2B;
Gene ID : 8396
mRNA Refseq : NM_003559
Protein Refseq : NP_003550
MIM : 603261
UniProt ID : P78356
Chromosome Location : 17q21.2
Pathway : 3-phosphoinositide biosynthesis, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Phosphatidylinositol signaling system, organism-specific biosystem; Phosphatidylinositol signaling system, conserved biosystem;
Function : 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; ATP binding; nucleotide binding; receptor signaling protein activity; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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