Recombinant Human PMEL protein, MYC/DDK-tagged
Cat.No. : | PMEL-190H |
Product Overview : | Recombinant Human PMEL fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 70.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | PMEL premelanosome protein [ Homo sapiens ] |
Official Symbol : | PMEL |
Synonyms : | PMEL; premelanosome protein; SIL, SILV, silver (mouse homolog) like , silver homolog (mouse); melanocyte protein PMEL; D12S53E; gp100; Pmel17; SI; melanocyte protein mel 17; silver, mouse, homolog of; melanocyte protein Pmel 17; melanosomal matrix protein17; silver locus protein homolog; melanoma-associated ME20 antigen; melanocytes lineage-specific antigen GP100; P1; SIL; ME20; P100; SILV; ME20M; ME20-M; PMEL17; |
Gene ID : | 6490 |
mRNA Refseq : | NM_006928 |
Protein Refseq : | NP_008859 |
MIM : | 155550 |
UniProt ID : | P40967 |
Products Types
◆ Recombinant Protein | ||
PMEL-191H | Recombinant Human PMEL Protein, GST-tagged | +Inquiry |
PMEL-2756H | Recombinant Human PMEL protein(371-440 aa), C-His-tagged | +Inquiry |
Pmel-4952M | Recombinant Mouse Pmel Protein, Myc/DDK-tagged | +Inquiry |
PMEL-2601H | Recombinant Human PMEL Protein, His-tagged | +Inquiry |
PMEL-1717H | Recombinant Human PMEL Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (4)
Ask a questionWe will provide you with the most suitable labels according to your needs.
Animals with PMEL gene deletions exhibit varying degrees of hyperpigmentation.
PMEL proteins play an important role in melanin synthesis and storage.
PMEL proteins are predominantly expressed in the hair follicles and skin of ducks.
Customer Reviews (3)
Write a reviewYour company offers a one-stop shop and the process from purchase to receipt of the protein was very smooth!
The purchased PMEL protein is suitable for WB experiments and I am satisfied with the results.
Friendly customer service and detailed answers to all the questions I asked!
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