Recombinant Human PMEL Protein (25-467 aa), His-tagged
| Cat.No. : | PMEL-1518H |
| Product Overview : | Recombinant Human PMEL Protein (25-467 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial. |
| Availability | May 22, 2026 |
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| Species : | Human |
| Source : | Yeast |
| Tag : | His |
| Protein Length : | 25-467 aa |
| Description : | Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 49.0 kDa |
| AA Sequence : | KVPRNQDWLGVSRQLRTKAWNRQLYPEWTEAQRLDCWRGGQVSLKVSNDGPTLIGANASFSIALNFPGSQKVLPDGQVIWVNNTIINGSQVWGGQPVYPQETDDACIFPDGGPCPSGSWSQKRSFVYVWKTWGQYWQVLGGPVSGLSIGTGRAMLGTHTMEVTVYHRRGSRSYVPLAHSSSAFTITDQVPFSVSVSQLRALDGGNKHFLRNQPLTFALQLHDPSGYLAEADLSYTWDFGDSSGTLISRALVVTHTYLEPGPVTAQVVLQAAIPLTSCGSSPVPGTTDGHRPTAEAPNTTAGQVPTTEVVGTTPGQAPTAEPSGTTSVQVPTTEVISTAPVQMPTAESTGMTPEKVPVSEVMGTTLAEMSTPEATGMTPAEVSIVVLSGTTAAQVTTTEWVETTARELPIPEPEGPDASSIMSTESITGSLGPLLDGTATLRLV |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Gene Name | PMEL premelanosome protein [ Homo sapiens ] |
| Official Symbol | PMEL |
| Synonyms | PMEL; D12S53E; gp100; Pmel17; SI; P1; SIL; ME20; P100; SILV; ME20M; ME20-M; PMEL17; |
| Gene ID | 6490 |
| mRNA Refseq | NM_001200053 |
| Protein Refseq | NP_001186982 |
| MIM | 155550 |
| UniProt ID | P40967 |
Not For Human Consumption!
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