Recombinant Human PSG5, His-tagged

• Cat.No.: PSG5-15894H
• Product Overview: Recombinant human PSG5 protein, fused to His tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 35-335aa
• Description: PSG5 is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSG5 function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1M Urea, 10% glycerol
• Molecular Mass: 36.4 kDa (324aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQVTIEAL PPKVSEGKDV LLLVHNLPQN LAGYIWYKGQ LMDLYHYITS YVVDGQINIY GPAYTGRETV YSNASLLIQN VTREDAGSYT LHIIKRGDRT RGVTGYFTFN LYLKLPKPYI TINNSKPREN KDVLAFTCEP KSENYTYIWW LNGQSLPVSP RVKRPIENRI LILPSVTRNE TGPYECEIRD RDGGMRSDPV TLNVLYGPDL PSIYPSFTYY RSGENLYLSC FAESNPPAEY FWTINGKFQQ SGQKLSIPQI TTKHRGLYTC SVRNSATGKE SSKSMTVEVS APSGIGRLPL LNPI
• Purity: >80% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PSG5 pregnancy specific beta-1-glycoprotein 5 [ Homo sapiens (human) ]
• Official Symbol: PSG5
• Synonyms: PSG5; pregnancy specific beta-1-glycoprotein 5; PSG; FL-NCA-3; PSBG-5; PS-beta-G-5; pregnancy-specific glycoprotein 5; pregnancy-specific beta 1 glycoprotein; pregnancy-specific beta-1 glycoprotein; Pregnancy-specific beta-1-glycoprotein-5; etal liver non-specific cross-reactive antigen 3
• Gene ID: 5673
• mRNA Refseq: NM_001130014
• Protein Refseq: NP_001123486
• MIM: 176394
• UniProt ID: Q15238
• Chromosome Location: 19q13.2