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Recombinant Human PTK7 Protein, DDK/His-tagged

Cat.No. : PTK7-669H
Product Overview : Recombinant Human PTK7(Ala31-Thr704), transcript variant 2, fused with DDK/His tag at C-terminal was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Source : HEK293 cells
Species : Human
Tag : DDK/His
Form : 1 x PBS, pH7.4, 10% glycerol.
Molecular Mass : 73 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PTK7 PTK7 protein tyrosine kinase 7 [ Homo sapiens ]
Official Symbol : PTK7
Synonyms : PTK7; PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7; CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; protein-tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7;
Gene ID : 5754
mRNA Refseq : NM_002821
Protein Refseq : NP_002812
MIM : 601890
UniProt ID : Q13308

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Does PTK7 have specific extracellular domains? 12/30/2021

Yes, PTK7 possesses extracellular domains, including a Wnt co-receptor domain, suggesting involvement in Wnt signaling pathways.

In which cellular processes does PTK7 participate? 11/07/2021

PTK7 is involved in diverse processes, including cell proliferation, migration, tissue morphogenesis, and planar cell polarity.

Are there potential therapeutic applications for PTK7? 10/29/2021

PTK7 is being explored as a potential therapeutic target, particularly in cancer treatment and tissue regeneration.

What role does PTK7 play in planar cell polarity? 04/10/2020

PTK7 plays a pivotal role in planar cell polarity, contributing to the alignment of cells and tissues during development.

What is the full name of PTK7? 06/04/2019

PTK7 stands for Protein Tyrosine Kinase 7.

What kind of protein is PTK7? 07/24/2018

PTK7 is a transmembrane receptor protein with tyrosine kinase activity.

Is PTK7 implicated in any diseases? 09/19/2016

Altered expression of PTK7 has been associated with various cancers, including colorectal cancer.

Customer Reviews (3)

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Reviews
09/09/2019

    We observed that results obtained with the product remained stable and reliable over long-term experiments.

    06/19/2019

      We appreciated that the product adhered to relevant regulatory standards, ensuring the ethical conduct of our experiments.

      02/12/2019

        The product's compliance with safety and ethical guidelines made it a responsible choice for our research endeavors.

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