Recombinant Human S100A8 & S100A9 Heterodimer Protein, His & Flag tagged

Cat.No. : S100A8 & S100A9-2217H
Product Overview : Recombinant Human S100A8 (NP_002955.2) (Met1-Glu93), fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; Human S100A9 (NP_002956.1) (Met1-Pro114), fused with a flag tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the S100A8 & S100A9 heterodimer was purified.
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Source : Insect Cells
Species : Human
Tag : His & Flag
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The recombinant human S100A8 & S100A9 heterodimer comprises 103 amino acids (S100A8) and 122 amino acids (S100A9). It has a calculated molecular mass of 12.2 kDa (S100A8) and 14.2 kDa (S100A9).
Protein Length : Met1-Glu93&Met1-Pro114
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 85 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do alterations in S100A8 expression impact cellular stress responses and aging? 03/03/2022

Changes in S100A8 expression impact cellular stress responses, with implications for aging and age-related diseases.

How does S100A8 contribute to the pathogenesis of cancer, especially in terms of tumor growth and metastasis? 12/12/2021

S100A8 contributes to cancer development, influencing tumor cell proliferation and metastatic potential.

What is the impact of S100A8 on wound healing and tissue repair mechanisms? 03/02/2021

S100A8 is involved in wound healing, affecting tissue repair and regeneration.

How does S100A8 interact with calcium ions and what are the implications for inflammatory processes? 01/18/2021

S100A8 binds calcium ions, modulating inflammatory processes and cytokine production.

How does S100A8 influence the development and progression of cardiovascular diseases? 11/01/2019

S100A8 affects cardiovascular disease development, impacting inflammation and vascular integrity.

What role does S100A8 play in the immune response, particularly in autoimmune diseases? 09/22/2019

S100A8 plays a significant role in the immune response, impacting the pathogenesis of autoimmune diseases.

What are the effects of S100A8 on skin homeostasis and the development of skin disorders? 10/06/2018

S100A8 influences skin health, playing a role in maintaining skin barrier function and in skin disorders.

Customer Reviews (3)

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Reviews
02/01/2022

    Dependable protein quantification, ensures experimental accuracy.

    10/29/2020

      Consistent western blot results, a lab essential.

      03/12/2020

        Expert protein engineering support, essential for our projects.

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