Recombinant Human TYK2 Protein, Myc/DDK-tagged

• Cat.No.: TYK2-03H
• Product Overview: Purified recombinant protein of Human tyrosine kinase 2 (TYK2), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 133.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate Bradford method
• Storage Buffer: 25 mM Tris-HCl, 100 mM glycine, 10% glycerol, pH 7.3

Gene Information

• Gene Name: TYK2 tyrosine kinase 2 [ Homo sapiens (human) ]
• Official Symbol: TYK2
• Synonyms: TYK2; tyrosine kinase 2; JTK1; IMD35; non-receptor tyrosine-protein kinase TYK2; EC 2.7.10.2
• Gene ID: 7297
• mRNA Refseq: NM_003331
• Protein Refseq: NP_003322
• MIM: 176941
• UniProt ID: P29597