Recombinant Human UNC119 Protein (1-240 aa), His-SUMO-tagged UNC119-1990H

Recombinant Human UNC119 Protein (1-240 aa), His-SUMO-tagged

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Recombinant Human UNC119 Protein (1-240 aa), His-SUMO-tagged

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Cat.No. : UNC119-1990H
Product Overview : Recombinant Human UNC119 Protein (1-240 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Neuroscience. Protein Description: Full Length.
Description : Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer,50% glycerol
Molecular Mass : 43.0 kDa
Protein length : 1-240 aa
AA Sequence : MKVKKGGGGA GTATESAPGP SGQSVAPIPQ PPAESESGSE SEPDAGPGPR PGPLQRKQPI GPEDVLGLQR ITGDYLCSPE ENIYKIDFVR FKIRDMDSGT VLFEIKKPPV SERLPINRRD LDPNAGRFVR YQFTPAFLRL RQVGATVEFT VGDKPVNNFR MIERHYFRNQ LLKSFDFHFG FCIPSSKNTC EHIYDFPPLS EELISEMIRH PYETQSDSFY FVDDRLVMHN KADYSYSGTP
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : UNC119 unc-119 homolog (C. elegans) [ Homo sapiens ]
Official Symbol : UNC119
Synonyms : UNC119; HRG4; POC7; POC7A; retinal protein 4;
Gene ID : 9094
mRNA Refseq : NM_005148
Protein Refseq : NP_005139
UniProt ID : Q13432

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