Recombinant Human UNC119 Protein (1-240 aa), His-SUMO-tagged
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| Cat.No. : | UNC119-1990H |
| Product Overview : | Recombinant Human UNC119 Protein (1-240 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Neuroscience. Protein Description: Full Length. |
| Description : | Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His-SUMO |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 43.0 kDa |
| Protein length : | 1-240 aa |
| AA Sequence : | MKVKKGGGGA GTATESAPGP SGQSVAPIPQ PPAESESGSE SEPDAGPGPR PGPLQRKQPI GPEDVLGLQR ITGDYLCSPE ENIYKIDFVR FKIRDMDSGT VLFEIKKPPV SERLPINRRD LDPNAGRFVR YQFTPAFLRL RQVGATVEFT VGDKPVNNFR MIERHYFRNQ LLKSFDFHFG FCIPSSKNTC EHIYDFPPLS EELISEMIRH PYETQSDSFY FVDDRLVMHN KADYSYSGTP |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. |
| Gene Name : | UNC119 unc-119 homolog (C. elegans) [ Homo sapiens ] |
| Official Symbol : | UNC119 |
| Synonyms : | UNC119; HRG4; POC7; POC7A; retinal protein 4; |
| Gene ID : | 9094 |
| mRNA Refseq : | NM_005148 |
| Protein Refseq : | NP_005139 |
| UniProt ID : | Q13432 |
◆ Recombinant Protein
| UNC119-6443R | Recombinant Rat UNC119 Protein | +Inquiry |
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◆ Lysates
| UNC119-502HCL | Recombinant Human UNC119 293 Cell Lysate | +Inquiry |
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UNC5AUNC5BUNC119UNC13DUNC5DUNC5CUNC84AUNC5CLUNC13AUNC45AUNC45BUNC119BUNC13BUNC50UNC13CUNC93AUnc79UNC80UNC93B1
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