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Recombinant Human USP1, MYC/DDK-tagged

Cat.No. : USP1-955H
Product Overview : Recombinant Human USP1 fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
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Cat. No. : USP1-955H
Description : This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
Source : HEK293 Cells
Molecular Mass : 88 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Storage buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage : Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
OfficialSymbol : USP1
Gene Name : USP1 ubiquitin specific peptidase 1 [ Homo sapiens ]
Synonyms : USP1; ubiquitin specific peptidase 1; ubiquitin specific protease 1; ubiquitin carboxyl-terminal hydrolase 1; Deubiquitinating enzyme 1; hUBP; Ubiquitin carboxyl terminal hydrolase 1; Ubiquitin carboxyl-terminal hydrolase 1; Ubiquitin specific peptidase 1; Ubiquitin thiolesterase 1; Ubiquitin-specific-processing protease 1; UBP; UBP1_HUMAN; USP 1; Usp1; hUBP; ubiquitin thioesterase 1; deubiquitinating enzyme 1; ubiquitin thiolesterase 1; ubiquitin carboxyl terminal hydrolase 1; ubiquitin specific processing protease 1; ubiquitin-specific-processing protease 1; UBP
Gene ID : 7398
mRNA Refseq : NM_001017415
Protein Refseq : NP_001017415
MIM : 603478
UniProt ID : O94782
Chromosome Location : 1p31.3
Pathway : DNA Repair; Fanconi Anemia pathway; Fanconi anemia pathway; Fanconi anemia pathway; Regulation of the Fanconi anemia pathway
Function : cysteine-type endopeptidase activity; peptidase activity; protein binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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