| Description : |
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
88 kDa |
| AA Sequence : |
MPGVIPSESNGLSRGSPSKKNRLSL KFFQKKETKRALDFTDSQENEEKAS EYRASEIDQVVPAAQSSPINCEKRE NLLPFVGLNNLGNTCYLNSILQVLY FCPGFKSGVKHLFNIISRKKEALKD EANQKDKGNCKEDSLASYELICSLQ SLIISVEQLQASFLLNPEKYTDELA TQPRRLLNTLRELNPMYEGYLQHDA QEVLQCILGNIQETCQLLKKEEVKN VAELPTKVEEIPHPKEEMNGINSIE MDSMRHSEDFKEKLPKGNGKRKSDT EFGNMKKKVKLSKEHQSLEENQRQT RSKRKATSDTLESPPKIIPKYISEN ESPRPSQKKSRVKINWLKSATKQPS ILSKFCSLGKITTNQGVKGQSKENE CDPEEDLGKCESDNTTNGCGLESPG NTVTPVNVNEVKPINKGEEQIGFEL VEKLFQGQLVLRTRCLECESLTERR EDFQDISVPVQEDELSKVEESSEIS PEPKTEMKTLRWAISQFASVERIVG EDKYFCENCHHYTEAERSLLFDKMP EVITIHLKCFAASGLEFDCYGGGLS KINTPLLTPLKLSLEEWSTKPTNDS YGLFAVVMHSGITISSGHYTASVKV TDLNSLELDKGNFVVDQMCEIGKPE PLNEEEARGVVENYNDEEVSIRVGG NTQPSKVLNKKNVEAIGLLGGQKSK ADYELYNKASNPDKVASTAFAENRN SETSDTTGTHESDRNKESSDQTGIN ISGFENKISYVVQSLKEYEGKWLLF DDSEVKVTEEKDFLNSLSPSTSPTS TPYLLFYKKLSGPTRTRRLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
