| Description : |
This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
109.1 kDa |
| AA Sequence : |
MAEGGAADLDTQRSDIATLLKTSLR KGDTWYLVDSRWFKQWKKYVGFDSW DKYQMGDQNVYPGPIDNSGLLKDGD AQSLKEHLIDELDYILLPTEGWNKL VSWYTLMEGQEPIARKVVEQGMFVK HCKVEVYLTELKLCENGNMNNVVTR RFSKADTIDTIEKEIRKIFSIPDEK ETRLWNKYMSNTFEPLNKPDSTIQD AGLYQGQVLVIEQKNEDGTWPRGPS TPNVKNSNYCLPSYTAYKNYDYSEP GRNNEQPGLCGLSNLGNTCFMNSAI QCLSNTPPLTEYFLNDKYQEELNFD NPLGMRGEIAKSYAELIKQMWSGKF SYVTPRAFKTQVGRFAPQFSGYQQQ DCQELLAFLLDGLHEDLNRIRKKPY IQLKDADGRPDKVVAEEAWENHLKR NDSIIVDIFHGLFKSTLVCPECAKI SVTFDPFCYLTLPLPMKKERTLEVY LVRMDPLTKPMQYKVVVPKIGNILD LCTALSALSGIPADKMIVTDIYNHR FHRIFAMDENLSSIMERDDIYVFEI NINRTEDTEHVIIPVCLREKFRHSS YTHHTGSSLFGQPFLMAVPRNNTED KLYNLLLLRMCRYVKISTETEETEG SLHCCKDQNINGNGPNGIHEEGSPS EMETDEPDDESSQDQELPSENENSQ SEDSVGGDNDSENGLCTEDTCKGQL TGHKKRLFTFQFNNLGNTDINYIKD DTRHIRFDDRQLRLDERFFLALDWD PDLKKRYFDENAAEDFEKHESVEYK PPKKPFVKLKDCIELFTTKEKLGAE DPWYCPNCKEHQQATKKLDLWSLPP VLVVHLKRFSYSRYMRDKLDTLVDF PINDLDMSEFLINPNAGPCRYNLIA VSNHYGGMGGGHYTAFAKNKDDGKW YYFDDSSVSTASEDQIVSKAAYVLF YQRQDTFSGTGFFPLDRETKGASAA TGIPLESDEDSNDNDNDIENENCMH TNTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
