Recombinant Human v protein, MYC/DDK-tagged
Cat.No. : | MAP2K1-167H |
Product Overview : | Recombinant Human MAP2K1(mutant D67N) fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 43.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MAP2K1 mitogen-activated protein kinase kinase 1 [ Homo sapiens ] |
Official Symbol : | MAP2K1 |
Synonyms : | MAP2K1; mitogen-activated protein kinase kinase 1; PRKMK1; dual specificity mitogen-activated protein kinase kinase 1; MAPKK1; MEK1; MEK 1; MAPKK 1; MAPK/ERK kinase 1; MAP kinase kinase 1; ERK activator kinase 1; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); MKK1; |
Gene ID : | 5604 |
mRNA Refseq : | NM_002755 |
Protein Refseq : | NP_002746 |
MIM : | 176872 |
UniProt ID : | Q02750 |
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◆ Lysates | ||
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◆ Assay kits | ||
Kit-1614 | MEK1 Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there are clinical trials exploring the efficacy and safety of MAP2K1 inhibitors in various cancers and other diseases.
Some diagnostic tests may analyze MAP2K1 mutations, especially in the context of cancer, to inform treatment decisions.
MAP2K1 mutations can serve as biomarkers in cancer diagnostics, aiding in the identification and classification of tumors.
MAP2K1 mutations can be associated with resistance to certain cancer therapies, making it important to understand its role in treatment response.
Yes, MAP2K1 inhibitors are being explored as targeted therapies in cancer treatment, aiming to block the abnormal signaling associated with MAP2K1 mutations.
Customer Reviews (3)
Write a reviewThe unmatched performance of the MAP2K1 protein in both ELISA assays and protein electron microscopy structure analysis showcases its versatility and reliability in various experimental settings.
The MAP2K1 protein finds extensive utility in protein electron microscopy structure analysis.
With its exceptional specificity and sensitivity, it enables precise and reliable detection of target molecules, making it a valuable tool in the field of diagnostic and research applications.
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